Background: Pott’s Spine, or spinal tuberculosis, is a severe form of extrapulmonary tuberculosis that can lead to debilitating deformities and neurological complications if not diagnosed and treated early. Public awareness and knowledge about Pott’s Spine, particularly in rural and semi-urban communities, remain limited, contributing to delayed healthcare-seeking behaviors. This study aims to assess the awareness and knowledge of Pott’s Spine among the community members of Hamirpur, Himachal Pradesh, to identify gaps and inform targeted health education interventions.Material and Methods: A descriptive, cross-sectional study was conducted among 400 residents of Hamirpur, Himachal Pradesh, using a structured questionnaire. Participants were selected through stratified random sampling. The questionnaire collected socio-demographic details and assessed knowledge of Pott’s Spine through 20 multiple-choice questions. Data were analyzed using descriptive statistics, with knowledge scores categorized as Very Good (>80%), Good (60–79%), Fair (41–59%), and Poor (<40%).Results:The study revealed a diverse socio-demographic profile, with 53.5% female participants and 65% residing in rural areas. Most participants (33%) were aged 26–35 years, and 27.5% had secondary education. Awareness of Pott’s Spine was encouraging, with 78% identifying it as tuberculosis of the spine and 82% recognizing its potential to cause deformities. However, knowledge gaps were evident in understanding diagnostic tools (63.5%) and early symptoms (66%). Preventive knowledge, such as the role of BCG vaccination (72%) and nutritional support (77.5%), was moderately high. Knowledge scores showed that 27% had very good awareness, while 27% and 10% demonstrated fair and poor knowledge levels, respectively.Conclusion: The study highlights a reasonable baseline understanding of Pott’s Spine among the Hamirpur community but identifies critical gaps in technical knowledge and early symptom recognition. Addressing these gaps through targeted health education initiatives and community engagement programs is crucial for improving early detection and management of Pott’s Spine. Enhanced awareness can contribute to reducing the burden of spinal tuberculosis and improving health outcomes in the region.