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Research Article | Volume 4 Issue 2 (July - Dec, 2024) | Pages 1 - 7
The Study of Investigate Suicide Among Adolescents In The Context of Cognitive Brain Change
 ,
 ,
1
Lincoln university College, Petaling Jaya Malaysia
Under a Creative Commons license
Open Access
Received
May 5, 2024
Revised
May 20, 2024
Accepted
June 20, 2024
Published
July 29, 2024
Abstract

One of the worst killers of American youth, suicide is a huge problem in China's public health system. Changes in adolescent suicide rates, especially among young women, have coincided with the current surge in the rate of suicide nationally. That's why it's so important for them to fully understand the many factors that might cause youth suicide attempts. By connecting the dots between the that underlies neurobiology and cognitive abnormalities connected to suicide behaviour and the clinical and psychosocial risk factors for suicide conduct, they may better understand the nature of the problem and perhaps develop more effective treatments. According to their hypothesis, there are many levels of explanation that might explain variations in suicidal conduct. These levels include growth-oriented biophysical (genomics, a proteome, epigenetics, immunology), and psychological/clinical. In an attempt to shed light on the connection between neurological, a genetic condition, and clinical data in the study of suicide, their model presents a unified the hypothesis to better understand this complex finding by integrating results from different fields of research on suicidality. Planning successful strategies to prevent suicide and suicidal thoughts requires an understanding of the complex interaction of biological, psychological, sociobiological, and medical risk factors.

Keywords
Introduction

Suicide and attempts at it are significant contributors to illness and death in the realms of mental wellness and public health. Industrialized nations, especially the United States, universally acknowledge that suicide ranks as the second most prevalent cause of mortality among young individuals. Based on the most recent CDC and the National Centre for Health Data briefly for 2019, suicide ranks as the second most common cause of death among those aged 15 to 24. Based on the latest statistical data provided by the Centre’s for Disease Control and Prevention (CDC), it is evident that the overall rate of suicide in the USA had a notable increase of 30% throughout the period spanning from 2000 to 2016. An increasing trajectory was observed across all age cohorts. Public and mental health specialists concur that teenage suicidality is a significant concern that requires attention from contemporary suicide prevention programs. Factors like as anxiety in interactions with others, loneliness, mental illness, drug misuse, and addictions may all play a role in the development of suicidal thoughts and actions. Therefore, it is crucial to possess a comprehensive understanding of the many factors that might potentially lead to teenage suicidality. The authors have endeavoured to condense the crucial protective and risk factors in this field, drawing on the findings of scientific literature in the fields of biological processes, neuroscience, neurobiology, and neuroimaging. <text>Their objective was to develop a comprehensive explanatory model for suicidality by analysing clinical data focused on suicidal diagnosis, prevention, and therapy. The World Health Organisation has documented a progressive rise in youth suicide rates over the last 50 years, making it the second most common cause of death globally, behind accidents. The alarming data underscore the urgent need to thoroughly examine and tackle the underlying factors contributing to suicide, particularly among the youth. The presence of symptoms of depression and feelings of solitude significantly increases the likelihood of suicide thoughts and conduct in adolescents. However, there are only a limited number of indicators that, when considered together, may accurately predict suicidal ideation or the progression to an actual suicide attempt. Examining the neurodevelopmental factors that lead to suicidal thoughts and actions might enhance their ability to predict and treat suicide (Barzilay, 2019).

Amongst those ages 10 to 24, suicide ranks as the second leading cause of death, surpassed only by unintentional fatalities. Identifying risk factors all through adolescence is crucial due to the increasing prevalence of thoughts of suicide and behaviour (STB) in this demographic. However, there is a limited number of suicide theories that specifically address the challenges faced by adolescents, since the majority of research just applies adult models to younger populations. The aforementioned phenomenon has the capacity to provide assistance, although it simultaneously presents an obstacle to the investigation of mechanisms that exhibit a stronger association with suicidal thoughts and behaviours (STBs) among teenagers, and which may have a more significant influence on the prevalence of suicide within this demographic. Extensive research spanning many decades has consistently shown that commonly examined demographic and clinical variables do not possess any discernible predictive value in relation to suicide-related outcomes, surpassing only random chance. In order to enhance the prevention of suicidal thoughts and behaviours (STB), there exists a need for doing research on supplementary transdiagnostic variables associated with suicide risk. The RDoC paradigm places its emphasis on elements that are shared across several unique mental illnesses and conceptualises those characteristics as constructs at many levels of study. Moreover, it has significant promise for elucidating hitherto unrecognised risk variables that might be targeted for preventative and therapeutic interventions (Burstein, 2019).

 

BACKGROUND OF THE STUDY:

The phenomenon of suicide is characterised by its intricate nature, as it is subject to the effect of a diverse array of causes, including internal as well as outside dimensions. The elevated risk of suicide seen in families with a high prevalence of suicidal behaviour underscores the significance of identifying potential variables that could be contributing to the familial dissemination of suicidal behaviour. In recent years, there has been an increased emphasis on the need of enhancing neurocognitive abilities. Neurocognitive impairments may serve as an endophenotype in the assessment of suicide risk. Furthermore, several studies have shown a correlation between sleep deprivation and neurocognitive deficits, namely a decrease in attentional abilities. Research suggests that those with inadequate attentional control are more prone to experiencing suicidal thoughts. This finding pertains to the capacity to focus on a single job without being easily distracted. Individuals who are classified as adults as well as adolescents with Spina Bifida (SB) exhibit heightened sensitivity towards these factors, along with a decreased threshold for distraction and an increased emotional sensitivity while processing inputs from their surroundings. Research has shown a correlation between inadequate organisational strategies used during the initial recording of information and challenges in retrieval, which subsequently heighten the susceptibility to suicide among individuals with impaired memory. The term "function" refers to a mathematical concept that describes the relationship between two sets of Deficiencies in executive function have been shown to be associated with challenges in controlling emotions, solving problems, and behavioural inhibition, ultimately leading to an increased vulnerability to self-destructive behaviours. Studies have shown that individuals who have suicidal ideation or have made suicide attempts exhibit distinct challenges in cognitive inhibition and decision-making processes. When individuals go from theoretical concepts to practical application, they may engage with many disciplines (Luciana, 2018).

 

Collectively, these data indicate a correlation between cognition and suicidal behaviour, underscoring the need of investigating alterations in cognitive processes associated with suicidal ideation. The Adolescence Brain Cognitive Growth (ABCD) StudyVR is a comprehensive longitudinal investigation conducted across many sites. This research focuses on the observation of children between the ages of 9 and 10, tracking their development from the start of puberty until the beginning of adulthood. The primary objective of the ABCD study is to examine the impact of early life experiences on future health outcomes and academic accomplishments. Therefore, the ABCD research offers valuable data for the analysis of risk variables associated with suicidal ideation and conduct among adolescents. The present research investigated the association between social intelligence (SI) and cognitive ability by using the baseline database from the ABCD approach project (the information version 2.0.1). Only a single study has been undertaken on the subject of sensory integration (SI) and neurocognition in children. In this study, investigators used the exploratory analytic technique to assess the participants' cognitive performance across a range of activities. The following conclusions are derived from prior research including individuals from both younger and older age groups. It was hypothesised that children with sensory integration (SI) would have a neurocognitive advantage compared to those without SI when assessed on measures of memory, focus, and executive function (Compton, 2019).

 

PROBLEM STATEMENT:

“Suicide is the leading cause of death among adolescents. While clinicians and researchers have begun to recognize the importance of considering multidimensional factors in understanding risk for suicidal thoughts and behaviors (STBs) during this developmental period, the role of puberty has been largely ignored.”

 

This study by examined Ortuno-Sierra adolescence is a developmental phase characterised by the transition from childhood to adulthood, including many changes in an individual's physical, mental, social, and neurological aspects. During this developmental stage, neurohormones have significant influence by regulating several crucial physiological and psychological processes, finally culminating in complete maturation necessary for engaging in productive labour and reproductive activities. Moreover, cohabitation with family members and associations with peer groups have a substantial influence on the formation of an individual, just as the crucial assimilation into the societal environment (Ortuno-Sierra, 2020).

 

RESEARCH OBJECTIVES:

  • To evaluate the leading cause of suicide in adolescents.

  • To identify the causes of cognitive dissonance associated with suicidal thought.

  • To find the level of effect of cognitive disorders on adolescents suicides.

  • To learn about the mental illness those are associated with the highest risk of suicide among adolescents.


LITERATURE REVIEW:

There exists a high correlation between suicidal ideation and behaviours and severe depression among teenagers. Therefore, it is important for individuals to possess a comprehensive understanding of the many elements that contribute to the heightened susceptibility of young individuals to engage in suicidal thoughts and actions. This review presents a comprehensive synthesis and critical analysis of the existing evidence pertaining to clinical and neurobiological aspects associated with teen suicide. The current research focuses on an explanatory framework that investigates the interplay between clinical trials and psychological risk factors in relation to the neurobiological and cognitive challenges associated with suicidal behaviour. This model holds promise in facilitating the identification of potential treatment interventions and possesses empirical significance. The authors contend that alterations in suicide ideation and actions may arise from a combination of developmental, biological (including genetics, proteomics, epigenetics, and immunology), psychological/clinical (such as childhood traumas), and environmental variables. Consequently, their primary objective is to provide a comprehensive theoretical framework that enhances the comprehension of suicidality by explaining the interconnectedness of various neurological, genetic, and clinical datasets within this domain. In order to effectively address suicide thoughts and conduct, it is crucial to consider a range of interconnected risk factors, including psychological, biochemical, sociobiological, and clinical dimensions. Moreover, a comparison is made between the neurological anomalies seen in adults and those observed in teenagers who have suicidal tendencies. The focus of research on the neuroscience of suicide should primarily revolve on either the examination of the functioning brain in live individuals or the analysis of postmortem brain tissue, notwithstanding the inherent constraints associated with the latter approach. Subsequent investigations have to concentrate on discerning the precise processes behind the manifestation of suicidal ideation and conduct among adolescent populations. Based on the provided information, clinicians may enhance their ability to identify and address suicidal tendencies in adolescents by considering several aspects such as impulsivity, aggression, diminished beneficial effects, social isolation, heightened thoughts of suicide, low tolerance for distress, and familial interactions. This understanding will assist individuals in formulating more effective techniques for the prevention and intervention of suicidal conduct among adolescents (Stewart, 2019).

 

To effectively prevent suicide, it is crucial to comprehend the complex interactions of psychological in nature biological in nature, sociobiological, and physiological risk variables. Additionally, they conduct investigations on the neurological parallels or differences that exist among suicidal thoughts in adults and adolescents. However, research pertaining to the brain, particularly post-mortem brain studies, is more suited for investigating the neurobiology behind suicide. Additional investigation into the underlying factors contributing to suicide ideation and behaviour among adolescents is warranted in future research endeavours. Acquiring this knowledge would be a significant advantage. Gaining comprehension of the development of the aforementioned disease, attaining a precise diagnosis, and implementing interventions that specifically address the adolescent's impulsivity, aggressiveness, diminished positive emotional state, social withdrawal, heightened negative cognition, maladaptive pain management, and familial dynamics are all vital factors. This type of information can assist medical professionals in formulating more efficacious techniques for addressing suicide ideation and behaviours among adolescents. Depressive disorders, particularly those of a severe kind, are a prominent contributor to suicide thoughts and conduct among the youth population. In order to fully comprehend the elements that contribute to the elevated propensity for suicide among young individuals, a comprehensive knowledge is required. In order to enhance comprehension of effective interventions for individuals at risk of suicide, the authors undertook an extensive examination of existing scholarly literature. This review focused on the explaining model for self-harm behaviours, which establishes connections between clinical and psychologically risk factors and the fundamental neurobiological and neuropsychological abnormalities associated with suicidal tendencies. To substantiate their assertions, they provide instances derived from their own experiences. The authors propose that variations in suicidal behaviour might be influenced by several factors, including biological aspects such as genetics, proteomics, epigenetics, and immunology, as well as psychological and clinical factors such childhood traumas, environmental factors related to development, and social variables. Therefore, the proposed model integrates data derived from neurological, genetic, and clinical investigations of suicidality to explain the apparent correlation across these diverse data sets (Miller, 2019).

CONCEPTUAL FRAMEWORK:
METHODOLOGY:

Sampling: The subjects in this study were 1329 adolescents sampled from the total population of China.

Data and Measurement: The data were collected during the first half of the annual year 2022. Adolescents were required. Questionnaire was distributed and quantitative analysis was implemented.

Statistical Software: MS-Excel and SPSS 25 Was used for Statistical analysis.

Statistical Tools: Descriptive analysis Was applied to understand the basic nature of the data. Validity and reliability of the data Was tested through Cronbach alpha and ANOVA.


RESULT:

Factor Analysis

Factor analysis is often used to verify the latent component structure of a set of measurement items (FA). It is believed that latent (or unseen) factors account for the observed (or measured) scores. Modeling is at the heart of accuracy analysis (FA). It focuses on modelling the interplay of seen occurrences, undiscovered causes, and measurement error. The Kaiser-Meyer-Olkin (KMO) Test may be used to determine whether the data is suitable for factor analysis. Both individual model variables and the whole model are tested to ensure sufficient sampling. Data analysis reveals the extent to which many variables may have some common variance. In most cases, a lower proportion indicates that the data is more amenable to factor analysis. KMO returns values between zero and one. The sample size is adequate if and only if the KMO value is between 0.8 and 1.0. A KMO of less than 0.6 indicates inadequate sampling and calls for adjustment. Some authors utilise the number 0.5 for this purpose; somewhere between 0.5 and 0.6, they'll have to use their discretion.

• KMO If it's close to zero, then means the sum of the correlations is tiny compared to the size of the partial correlations. To restate, large-scale correlations are a significant obstacle to component analysis. Here are Kaiser's minimum and maximum standards: Kaiser's minimum and maximum standards are as follows. Faltering between 0.050 and 0.059.

Below-average (0.60-0.69) In the middle school level, typically, With a quality point value between 0.80 and 0.89. Incredible diversity exists between 0.90 and 1.00.

 

KMO and Bartlett's Test:

KMO and Bartlett's Test

Kaiser-Meyer-Olkin Measure of Sampling Adequacy.

.964

Bartlett's Test of Sphericity

Approx. Chi-Square

3237.983

df

190

Sig.

.000

 

Assessing the data's suitability for factor analysis is the first step in exploratory factor analysis (EFA). According to Kaiser's proposal, the KMO (Kaiser-Meyer-Olkin) measure of sample adequacy coefficient value must be more than 0.5 in order to conduct factor analysis. To explain, KMO is an abbreviation for the Kaiser-Meyer-Olkin measure of the statistical significance of a sample. In this study, the KMO value for the information used was .964. Bartlett's test of sphericity also indicated a 0.00 significance level.

 

Test for Hypothesis

In the context of scientific discourse, the phrase "posing a hypothesis" pertains to the process of formulating a conjecture or supposition with the aim of initiating further discussion and, eventually, conducting empirical investigations to ascertain the degree of plausibility associated with the conjecture or supposition. Following the formulation of a viable hypothesis, the subsequent step in the scientific methodology is doing a comprehensive examination of existing literature. The observed outcomes align precisely with the anticipated outcomes posited by the hypothesis. A hypothesis is regarded as such when it serves as a proposed solution to the primary research question of a study. Depending on the extent of the research, it may be necessary to formulate a substantial quantity of assumptions, each of whom would undergo empirical examination.

 

Dependent Variable

Suicide in Adolescents:

Suicide may be defined as the act of intentionally causing one's own death. It has the potential to provide solace for individuals who are undergoing distress or events that elicit distress. The act of an individual intentionally ending their own life is often referred to as "dying by suicide," as opposed to the phrase "committing suicide" which has historically been used. An individual who engages in a deliberate endeavour to end their own life but does not succeed is often referred to as having made an "attempted suicide." Suicide is the act of intentionally terminating one's own life using self-inflicted means or engaging in behaviours that result in fatal consequences. Individuals who engage in suicide tend to have a high prevalence of severe depression and hold the erroneous belief that suicide is their exclusive means of alleviating their distress.

 

Independent Variable

Cognitive Brain Change:

One of the primary cognitive changes that manifest as a natural consequence of the ageing process is a reduction of effectiveness on cognitive activities that need rapid information processing or transformation, ultimately impacting the ability to make timely decisions. The observed alterations include reductions in indices related to the velocity of cognitive processing, capacity of memory storage, and executive cognitive performance.

 

Factor

Negative thinking patterns

Negative thoughts refer to cognitive processes that include negative judgements, expectancies, and attributions towards one's own self, others, or the globe at large. These ideas are often accompanied by unpleasant feelings and may lead to undesirable behavioural, physiological, and physical consequences.

 

The Relationship Between Negative Thinking Patterns And Suicide In Adolescents

Negative thoughts include cognitive processes characterised by negative assessments, expectations, and attributions directed towards oneself, others, or the global context. These concepts are often accompanied by negative emotions and may result in unfavourable behavioural in nature, physiological, and physical outcomes. The term "suicide" may be characterised as the deliberate act of inflicting one's own demise. This has the capacity to provide comfort to persons experiencing discomfort or experiences that generate distress. The deliberate act of a person terminating their own existence is often denoted as "dying by a suicide," in contrast to the previously used word "committing suicide" that has been prevalent in historical usage. An person who actively pursues the act of intentionally terminating their own life, however does not achieve the desired outcome, is frequently referred to as being involved in an "attempted suicide." Suicide refers to the deliberate act of ending a human life using self-inflicted methods or participating in actions that lead to deadly outcomes. Individuals who partake in suicidal behaviour often exhibit a significant incidence of serious depression and possess the mistaken conviction that taking their life is their only recourse for mitigating their anguish.

 

On basis of the above discussion, the researcher formulated the following hypothesis, which was analysed the relationship between negative thinking patterns and suicide in adolescents.

 

H01: “There is no significant relationship between negative thinking patterns and suicide in adolescents.”

H1:  “There is a significant relationship between negative thinking patterns and suicide in adolescents.”

Description: Table

Description automatically generated

Doing a multiple regression analysis in SPSS Statistics produced many output tables. Assuming that none of the assumptions were violated, this part solely discusses the three crucial tables that are required to adequately understand the outcomes of the multiple regression technique that was employed to analyse their data. This method was used to their company's data. While analysing their data for the eight assumptions required to do multiple regression, it is important to understand the conclusion, and this study, which is included in their enlarged lesson, provides a thorough description of what must be done. Before beginning the multiple regression process, a number of conditions must be satisfied.

 

 

Description: Table

Description automatically generated

The basic equation that may be used to anticipate disruptive technology based on Impulsivity, Negative thinking patterns, Perfectionism, Rumination: The likelihood of including essential components, Suicide in Adolescents= 1.677+ (9.343E-7 x H1_Mean (Negative thinking patterns)

 

CONCLUSION:

Adolescents who have had adverse experiences are at an increased likelihood of developing and managing mental health issues in the future. Additionally, they may have difficulties in achieving financial stability, establishing social connections, and maintaining physical well-being. Furthermore, these individuals may exhibit a propensity for engaging in hazardous or unlawful behaviours, as well as an elevated susceptibility to involvement in additional negative circumstances. Therefore, the prevention of such an occurrence will effectively mitigate the financial burden and long-term disability. The investigation of adolescents' utilisation and the examination of neurocognitive processes, including cognitive regulation, rewarding responsiveness/valuation, and negative urgency, are still in their nascent stages as seen by the limited body of research available. Furthermore, the current studies often yield conflicting results. Further investigation is required for these neurocognitive processes as they have the potential to function as early indicators of suicide risk. Specifically, research has shown that those who are not directly impacted by suicidal thoughts and behaviours (STBs), but possess a heightened susceptibility to them, have deficits in certain cognitive control abilities and rewarding responsiveness that are similar to those seen in children currently experiencing STBs. Furthermore, the discoveries made by researchers have the potential to impact the development of novel therapeutic approaches as they gain a deeper understanding of the distinct neuropsychological characteristics shown by teenagers who are at a heightened risk for [the specified condition]. A recent study conducted by Peckham and Johnson highlights that individuals with a heightened susceptibility to impulsivity driven by emotions may have advantages from participating in an emotional control training programme consisting of six sessions. This programme aims to assist these individuals in regulating their impulsive tendencies. In light of current research, it is evident that the use of neurocognitive processes informed by empirical studies has significant promise in augmenting the safety and overall well-being of adolescents. This approach involves the identification of risk adolescents and pre-teens by scientifically grounded methods, followed by the implementation of pioneering and effective early interventions.

 

LIMITATION:

Quantitative approaches include the use of models of mathematics, formulas, and other mathematical formulas that are predicated upon a certain set of assumptions. The relevance of these presumptions to other contexts is uncertain. Failure to heed this warning might lead to catastrophic outcomes resulting from the improper use of quantitative methodologies. Due to the occasional need for the expertise of qualified professionals, the use of quantitative approaches might incur significant costs. Due to the perceived lack of value in several applications, even prominent corporations use quantitative approaches on an infrequent basis. Managers often rely on their sense of intuition and previous experiences when making choices, prioritising subjective factors above objective data. The precision of quantitative methods may be compromised by many frequent problems, such as inadequate data availability, inconsistent definitions, suboptimal sample selection, improper methodological approaches, unsuitable comparisons, and ineffective presentation techniques. Due to the intrinsic intangibility and non-measurable nature of qualitative events, quantitative approaches are inadequate for analysing such occurrences. The methodologies used in this study do not account for intangible factors such as a manager's competence, disposition, or enthusiasm. However, it is possible to implement the tactics indirectly by transforming qualitative assertions into numerical ones. The assessment of a managers level of intellect, for example, may be determined by the extent to which they are scored on key personal attributes.

REFERENCES:
  1. Barzilay, R., Calkins, M. E., Moore, T. M., Boyd, R. C., Jones, J. D., Benton, T. D., … Gur, R. E. (2019). Neurocognitive functioning in community youth with suicidal ideation: Gender and pubertal effects. The British Journal of Psychiatry : The Journal of Mental Science, 215(3), 552–558.

  2. Burstein, B., Agostino, H., & Greenfield, B. (2019). Suicidal attempts and ideation among children and adolescents in US Emergency Departments, 2007–2015. JAMA Pediatrics, 173(6), 598–600.
    Compton, W. M., Dowling, G. J., & Garavan, H. (2019). Ensuring the best use of data: The ado-

  3. adolescent brain cognitive development study. JAMA Pediatrics, 173(9), 809–810.

  4. Luciana, M., Bjork, J. M., Nagel, B. J., Barch, D. M., Gonzalez, R., Nixon, S. J., & Banich, M. T. (2018). Adolescent neurocognitive development and impacts of substance use: Overview of the adolescent brain cognitive development (ABCD) baseline neurocognition battery.

  5. Ortuno-Sierra, J., Aritio-Solana, R., Dıez Gomez del Casal, A., & Fonseca-Pedrero, E. (2020). Neurocognitive functioning in adolescents at risk for suicidal behaviors. Archives of Suicide Research. Advance online publication.

  6. Stewart, J. R. (2019). Neurocognitive Processes Implicated in Adolescent Suicidal Thoughts and Behaviors. Current Behavioral Neuroscience Reports, 1-9.

  7. Miller, A. &. (2019). Adolescent Suicide as a Failure of Acute Stress-Response Systems. Annual Review of Clinical Psychology, 1-26.

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