The purpose of this study is to determine the structural model of intellectual capital, capital structure, ownership structure, firm size, profitability, and manufacturing firm value. The sample used is manufacturing companies listed on the Indonesia Stock Exchange. The period 2017-2019. The sampling in this study uses purposive sampling, which is based on criteria that include manufacturing companies recorded during the 2017-2019 period, manufacturing companies using rupiah currency, manufacturing companies that report periodic financial reports. The data analysis technique used is the Structural Equation Model - Partial Least Square (SEM-PLS), while the mediation test uses the Variance Accounted For (VAF) method. The results of this study indicate that the inner model analysis contains 10 hypotheses from 13 accepted hypotheses. Profitability, intellectual capital, capital structure, ownership structure, firm size, have a significant positive effect on firm value, while intellectual capital, capital structure, ownership structure, firm size have a significant positive effect on profitability. Profitability can mediate Intellectual Capital to Firm Value, and Profitability Mediation Firm Size to Firm Value. However, the novelty in this study shows that profitability cannot mediate capital structure on firm value and profitability cannot mediate ownership structure on firm value.