The study examines entrepreneurship orientation on the profitability of telecommunication business in Taraba state with the following objectives; (i) Examine the effects of Proactiveness on profitability of Airtel Networks LTD(ii) Determine the effects of innovation on profitability of Airtel Networks LTD (iii)Evaluate the effect of risk taking on the profitability of Airtel Networks LTD. The survey research design was employed for the study this was influenced by the research problem and its corresponding research question. The choice of survey research design was further considered appropriate because according to Zikmund, Babin, Carr and Griffin, (2012. the Population of the study were 270 staff of airtel network Limited. The sample size was 162 was drawn. Quantitative data collected through the copies of the questionnaire were analyzed using descriptive and inferential statistics. Statistical Package for Social Sciences SPSS 21.0 was used to analyze. The findings revealed that the three elements of entrepreneurship orientation taken together significantly affected profitability of telecommunication business (t = 9.781, sig = 000). However, the results indicate that the three elements of entrepreneurship orientation taken together accounted only 0.11% toward variations in profitability of telecommunication business (Adjusted R2 = 011). This means that the remaining 99.9% is a contribution of other factors not included in this study. This signifies that, the factors related to entrepreneurship orientation are important in determining the profitability of telecommunication business, whereas many other factors as well are important.