Study on The Mechanism of Anti-Colon Cancer Action of Epigallocatechingallate (EGCG): A Research Progress
Colorectal cancer is a prevalent malignant tumor within the digestive system, characterized by a complex and varied pathogenesis.Epigallocatechin gallate (EGCG), the primary active ingredient in green tea, has garnered extensive attention in recent years due to its anti-colorectal cancer properties. Research has demonstrated that EGCG exerts its anti-colorectal cancer effects via multiple signaling pathways, primarily by inhibiting cancer cell proliferation, inducing apoptosis and autophagy, suppressing cancer cell invasion and metastasis, combating tumor angiogenesis, modulating associated signaling pathways, and Boosting sensitivity to chemotherapy medications. This article reviews relevant literature both domestically and internationally to discuss the mechanisms of EGCGs anti-colorectal cancer actions, providing a reference for future research and clinical application in oncology.