The current research aims to identify adipose tissue hormones and their relationship with certain diseases such as diabetes and high blood pressure, Adipose tissue essential for maintaining physiological function and serves as an energy reservoir, divided in two types: - white adipose tissue and brown adipose tissue. Adipose tissue hormones have various important functions that regulate energy, insulin secretion, inflammation, blood pressure, glucose metabolism, including chemerin, adiponectin, resistin, and visfatin. These hormones, particularly chemerin, enhance insulin-dependent glucose uptake in fat cells, indicating chemerin's involvement in glucose balance. Ithas also been associated with the high blood pressure. Adiponectin plays role in controlling insulin sensitivity and increasing fat metabolism. Decreased levels are linked to diabetes patients and high blood pressure. Additionally, resistin, visfatin hormones contribute to occurrence of diabetes and high blood pressure.