Background: Giant Lumbar Disc Herniation (GLDH) is a rare condition. Its treatment could be surgical or non-surgical. We describe in this study the surgical management of patients with GLDH in Sylvanus Olympio teaching hospital of Lomé (Togo). Patients and Methods: We conducted a retrospective and descriptive study between September 2017 and October 2020. We included in the study adult patients presented with radicular pain symptoms or cauda equina syndrome, with lumbar disc herniation in the canal superior to 50% of the sagittal diameter of the lumbar spine. Results: Thirteen patients were operated on from a GLDH. This patient population was composed of 9 men (69.2%) and four women (30.8%). The mean age of the patient population was 43.23±6.723 years (range 33-55). The anatomical location of a herniated disc was centrally in 8 patients (61.5%). The level of the GLDH was between L4-L5 in 69.2 % cases (n = 9) and L5-S1 in 30.8% (n = 4). There was no complication during surgery. Evolution was graded as excellent in 76.9 % cases (n = 10) and good in 23.1% (n = 3). Conclusion: GLDH is a distinct entity compared with smaller herniations. Patients can develop cauda equina syndrome. Surgery has good results in our conditions.