Kikuchi disease, also known as histiocytic necrotizing lymphadenitis or Kikuchi Fujimoto disease (KFD), is a rare inflammatory condition with an unknown etiology that is self-limiting. The disease primarily affects young individuals, including children. A correct diagnosis is essential, as the condition can be mistaken for tuberculosis or lymphoma. We present the case of a 22-year-old female adolescent who presented with cervical lymphadenopathy. The remainder of the physical examination was unremarkable. Laboratory investigations yielded normal results. An excisional biopsy was performed, and the histopathologic examination revealed Kikuchi disease. The patient was treated and fully recovered after a few weeks. Histopathology is an accurate diagnostic option. Despite the rarity of Kikuchi's disease, clinical practitioners should consider it to avoid errors in therapy that could harm patients.