Rosai- Dorfman disease (RDD) also known as sinus histiocytosis with massive lymphadenopathy or sometimes as Destombes- Rosai- Dorfman disease is a rare disorder of unknown cause that is characterized by abundant histiocytes in lymph node or other locations including skin,  sinuses, breast and heart . We present a case of 64 year old female presented with massive cervical lymphadenopathy diagnosed by histocytopathology..