One of the problems facing public health is the control of Crimean-Congo hemorrhagic fever. It is a zoonotic virus that can infect the two humans and animals and occasionally result in mortality. Because of the endemic's recurrence in some regions, which called for more factual and documented information about it, this review aimed to gather the most important details regarding this virus. The infectious virus is made up of a segmented negative sense ribonucleic acid genome particle in globular shape encased in an infected viral glycoprotein-containing lipid structure. Diseases are frequently spread via ticks through blood or tissue from humans or animals. When there are mammals present, regardless of size, such as cattle and rabbits, the causative virus can spread quickly. Unlike in animals, where it is asymptomatic, in people it results in a high fever and hemorrhagic condition. Precautionary steps to manage tick vectors in endemic countries are recommended, as is fostering collaboration among clinical veterinary, medical, and ecology specialists.