Background: Bacterial co-infections in COVID-19 patients can lead to increased morbidity and mortality, necessitating prompt recognition and appropriate management.  Aim: The study aimed to characterize bacterial infections in COVID-19 patients, providing valuable insights into co-infections and their clinical implications. Materials and Methods The study conducted in Kirkuk city from March 10, 2022, to September 1, 2022, aimed to investigate bacterial infections in COVID-19 patients admitted to Al-Shifaa Epidemiological Hospital. The study included 104 individuals of different age groups and sexes who tested positive for COVID-19 and required hospitalization. The severity of COVID-19 was determined by specialized physicians based on internal medicine practices and CT scan results. Data were collected through interviews using a structured questionnaire to gather demographic characteristics and clinical presentations of the patients. COVID-19 diagnosis was confirmed using WHO criteria and RT-PCR of nasopharyngeal specimens following approved protocols. Respiratory samples (nasopharyngeal swabs) were collected under medical supervision for further analysis. The cultural diagnosis involved studying the color, shape, size, edge, and height of the growing colonies to identify the bacteria. Different culture media were used for this purpose, such as the solid MacConkey medium to differentiate fermented lactose colonies from non-fermented ones. Another medium, the solid chrome medium, was used to diagnose bacterial growth based on specific colors associated with each bacteria. Results: The study investigated the relationship between COVID-19 severity and various factors, including age, sex, body mass index (BMI), comorbidities, and bacterial infections. The findings indicated that severe COVID-19 cases were more prevalent among elderly patients (>57 years) and those with obesity, diabetes, respiratory problems, chronic kidney disease, cerebrovascular diseases, and autoimmune diseases. However, pregnancy did not show a significant association with severe COVID-19. Regarding clinical features, severe COVID-19 cases were more likely to present with dyspnea, headache, anosmia, and ageusia. Among the bacterial infections, Enterococcus faecalis was the most frequently isolated bacteria in COVID-19 patients, followed by Klebsiella pneumoniae and Staphylococcus aureus. Among the bacterial isolates, Enterococcus faecalis shows the highest occurrence in severe COVID-19 cases, constituting 64.52% of positive cases in this category. 64.71 percent of mild COVID-19 patients had Klebsiella pneumoniae. In mild, moderate, and severe COVID-19 instances, Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa, Staphylococcus epidermidis, and Proteus mirabilis are found in varying amounts. Cephalothin and Imipenem showed great sensitivity against all isolates without resistance. Clindamycin and Carbenicillin were completely insensitive to all isolates.  Conclusion: In severe COVID-19 instances, bacterial co-infections must be identified. Severe cases had Enterococcus faecalis, highlighting the necessity for specific antibiotics. Drug stewardship reduces antibiotic resistance and improves patient outcomes. More study is needed to understand COVID-19 patients' viral-bacterial interactions.