Background: Septic arthritis is a severe joint infection predominantly affecting children, leading to significant morbidity if untreated. Early recognition and timely intervention are crucial to prevent long-term complications, such as joint deformities and mobility loss. Despite its clinical significance, public awareness of septic arthritis remains limited, particularly in rural settings like Hamirpur, Himachal Pradesh. This study aims to assess the knowledge and awareness of septic arthritis among the general public to identify gaps and inform targeted educational interventions.Material and Methods: This cross-sectional study was conducted in Hamirpur, Himachal Pradesh, over three months, involving 400 participants. A structured questionnaire, divided into socio-demographic details and knowledge assessment on septic arthritis, was used for data collection. The knowledge assessment covered symptoms, risk factors, diagnostic methods, treatment, and preventive measures. Responses were scored and categorized into four levels: very good, good, fair, and poor. Descriptive statistics were used to analyze the data, and chi-square tests assessed the relationship between socio-demographic factors and knowledge levels.Results: The study population consisted of 45.5% males and 54.5% females, with 64.0% residing in rural areas. Educational attainment was diverse, with 27.0% completing secondary school and 10.5% holding postgraduate degrees. Knowledge assessment revealed that 71.0% of participants identified septic arthritis as a joint infection, and 78.0% were aware of its risk factors. However, only 62.0% were familiar with diagnostic methods, and 61.0% understood the role of surgery in treatment. Knowledge score analysis showed that 27.0% of participants demonstrated very good knowledge, 34.0% good knowledge, while 27.0% and 12.0% had fair and poor knowledge, respectively.Conclusion: The study highlights moderate awareness of septic arthritis among the general public in Hamirpur, with significant gaps in technical and preventive knowledge. These findings underscore the need for targeted educational initiatives focusing on symptom recognition, diagnostic tools, and preventive measures, particularly in rural areas. Culturally tailored health campaigns and community engagement are essential to improve public understanding and reduce the burden of septic arthritis in children.