Immunological Detection of Human Papillomavirus (HPV) Antigen using ELISA from women with genital warts in Mosul/Iraq
The term "genital warts" refers to innocent proliferative illnesses exhibiting outward manifestations, including a vulva, vagina, or cervix containing one or more papules. These Sexually Transmitted Infections (STIs) are typically brought on by HPV genotypes 6 and 11 which considered as Low Risk . a one hundred fifty sample (biopsy and blood) collected from women with genital warts who visit Al-Zahrawy Private Hospital and Mosul General Hospital in Mosul, Iraq. The diagnosis of infection and the immunological study were done for the HPV-positive samples by Polymerase Chain Reaction (PCR) to detect the HPV antigen by Enzyme-Linked Immuno Sorbent Assay (ELISA). The findings showed that 3% were positive for the HPV antigen in biopsy samples and zero for blood samples. So the immunological detection by ELISA was not efficient in detecting the HPV antigen, nor in sera or tissue samples.