Background: Polycystic Ovary Syndrome (PCOS) is a common endocrine disorder affecting women of reproductive age, with significant implications for reproductive, metabolic, and psychological health. Despite its prevalence, awareness and understanding of PCOS remain limited, particularly in rural and underserved regions. This study aims to assess the knowledge and awareness of PCOS among women of reproductive age in Kangra District, identifying gaps to guide targeted educational initiatives.Material and Methods: This cross-sectional study was conducted from July to September 2024 among 400 women aged 18–45 years residing in Kangra District. Participants were selected using stratified random sampling, and data were collected through a pre-validated structured questionnaire. The questionnaire assessed socio-demographic characteristics and knowledge of PCOS, including its symptoms, risk factors, complications, and preventive measures. Responses were categorized into knowledge levels: Very Good (>80%), Good (60–79%), Fair (41–59%), and Poor (<40%). Descriptive and inferential statistical analyses were performed using SPSS v26.0.Results: The study revealed diverse socio-demographic profiles, with 45% of participants aged 26–35 years, 58% educated to at least secondary school level, and 68% residing in rural areas. Knowledge assessment showed that 78% recognized PCOS as a hormonal disorder, 74% identified irregular periods as a symptom, and 71% understood its link to infertility. However, awareness of lifestyle management (63%) and long-term complications such as diabetes (61.5%) was limited. Knowledge scores categorized 28% as "Very Good," 35% as "Good," 25% as "Fair," and 12% as "Poor."Conclusion: The findings highlight foundational awareness of PCOS but reveal critical gaps in understanding its holistic management and long-term implications. Targeted educational initiatives emphasizing lifestyle modifications, early detection, and comprehensive management are essential. Integrating PCOS awareness into community health programs and leveraging digital platforms can enhance outreach and empower women to take proactive steps toward their reproductive health.