srjalsSRJALSSRJALS2788-9386https://doi.org/10.47310/srjals.2022.v02i02.009Effect of Oral Administration of Spirulina platensis and Silver Nanoparticles on the Health Status of Blood Pictures and White Blood Cells in Healthy and Hyperlipidemia AnimalsSaad DhaminOleiwiKarkazM. ThalijCollege of Agriculture, Tikrit University, Tikrit, IraqThe study was conducted in the laboratories of the Department of Food Sciences-College of Agriculture and in the animal house of the College of Veterinary Medicine at Tikrit University for the period from 1/9/2021 until 29/11/2021 with the aim of identifying the therapeutic ability of S. platensis at a concentration of 150 mg/ml and AgNPs at a concentration 10 mg/ml on the health status of blood pictures and white blood cell in healthy and experimental hyperlipidemia. The results showed a significant increase in the values of Red Blood Cells (RBCs), Hemoglobin estimation (Hb) and the proportion of Hematocrit (Hct) for healthy groups given orally of AgNPs (T1) and Spirulina (T2) or of both (T3) and for groups treated by oral administration of AgNPs (T5) and Spirulina (T6) or both (T7) compared to the T4 infestation group whose values for the above criteria were 6.49×106/mm3, 11.16 g/dl, 37.86%, respectively. As for the values of MCH and MCHC, they decreased significantly in the healthy and treated groups compared to the infection group. Oral administration of AgNPs and Spirulina also caused a significant decrease in the healthy groups T1, T2, T3 and treated T5, T6 and T7 groups compared with the infected group in total and differential numbers of white blood cells.