srjmsSRJMSSRJMS2788-9483https://doi.org/ 10.47310/srjms.2021.v01i01.015A Hospital Based Study to Find Association of Pulmonary Function Indices and Arterial Blood Gas Status with Pulmonary Artery Hypertension (PAH) among Interstitial Lung Diseases (Ilds) PatientsVirSinghJunior Resident, Department of Pulmonary Medicine, IGMC, Shimla (HP), IndiaBackground: Pulmonary hypertension (PH) can develop in interstitial lung disease (ILD), and contributes to increased morbidity and mortality. The present study was done to evaluate the association of pulmonary function indices and arterial blood gas status with Pulmonary artery hypertension (PAH) among Interstitial Lung Diseases (ILDs) patients. Material and Methods: This cross-sectional study was conducted at Indira Gandhi Medical College, Shimla from July 2018 to June 2019. All consecutive patients of all types of ILDs, attending the outpatient services of the Department of Pulmonary Medicine, IGMC Shimla were enrolment and subjected to focused socio-demographic, Pulmonary artery hypertension (PAH) , pulmonary function indices and arterial blood gas status .Data was analyzed using Epi info V7 software by applying appropriate statistical tests. Results: The present study includes 50 patients of different types of ILD. Out of 50 patients, 44 (88%) had PAH. Out of 50 patients, the mean sO2 and paO2 were 82.50+10.79 mmHg and 55.77+10.30mm Hg respectively. Among patients who had PH the mean value of sO2 and paO2 were 82.09+11.11 mmHg and 55.54+10.54 mmHg respectively, with a p value of 0.47 and 0.31.Out of 50 patients 32 (64%) patients had sO2 <88mmHg and 22(54%) patients had paO2 <55mmHg. Among those patients who had PH sO2 < 88mmHg and paO2 <55mmHg were 30(68.18% and 25(46.82%)) respectively, with a p value of 0.11 and 0.25. Among 50 patients the mean value of six-minute walk distance was 311.42+122.55meter, the mean value was 307.52+117.54(m) among the PH group, with a p value of 0.54. Out of 50 patients, 30(60%) patients were walked less than 350meters, among these 26(59.09%) patients had PH, with a p-value of 0.54.Among patients with PH group, 6 (13.64%) had not performed PFT, 4 (9.09%) had an obstruction, 26 (59.09%) had restriction, 3 (6.82%) had mixed and 5(11.36%) had normal PFT, with a p- value of 0.83 Conclusion: There was very high prevalence of PAH among ILD Patients. Among patients who had PAH, mean value of sO2 and paO2 and the mean value of six-minute walk distance was lower than those who didn’t had PAH. Also, the patients of PAH mostly had restriction pattern in PFT.