srjalsSRJALSSRJALS2788-9386https://doi.org/10.47310/srjals.2025.v05i02.004The Effect of Oxidative Stress and its Role in Myocardial InfarctionSanaaMohamed MorshedTikrit University, College of Education for Girls, Department of Biology, Open College of Education, Kirkuk Study Center, IraqThe present study was designed to learn the effect of oxidative stress in patients registered with heart diseases by conducting some tests and measurements of some enzymes such as: aspartate aminotransferase (AST) concentration, Creatine phosphokinase (CPK),. (85) blood samples were selected from (60 male and female patients and 15 healthy individuals). The samples were divided into four groups: The first group: included patients with myocardial infarction, numbering (30) patients (males and females), whose ages ranged between (35 - 89) years. The second group: included patients with angina pectoris, numbering (20) patients (males and females), whose ages ranged between (32 - 85) years. Control group: This group included (15) individuals (males and females), ranging in age from (30-57) years. The current study showed the following results: There was a significant increase at a significance level (p<0.05) in the concentration of aspartate aminotransferase (AST) in the angina group in males and in the heart failure group in females, and in these two groups within the group (males + females), male gender, diabetics and smokers. A significant increase at a significance level (p<0.05) in the concentration of the enzyme creatine phosphokinase (CPK) in patients with myocardial infarction, males and females (males + females), male gender, age group (80-89 years), patients with high blood pressure, diabetes and smokers.