iarjmsIARJMSIARJMS2708-3594https://doi.org/10.47310/iarjms.2023.v04i01.047An Institutional Study to Compare the Therapeutic Effect of Intermittent and Continuous PhototherapyGauravKishoreSujaykumarEBackground and Objectives: Neonatal hyperbilirubinemia is treated safely and effectively with phototherapy. Despite its international applicability, Turning the newborn is thought to be one of the ways to improve, but despite its widespread use, issues about how to maximise effectiveness remain unanswered. Sensory-neural hearing loss, athetoid spasticity and abnormalities of the gaze and vision are all symptoms of the condition known as kernicterus, which is characterised by severe infant hyperbilirubinemia. Furthermore, it might be connected to mental disability. This study aimed to compare the efficacy of intermittent and continuous phototherapy. Methods: From March 2021 to September 2022, 210 newborns participated in the study at tertiary health care center, Banglore. The inclusion criteria included weight greater than 2500 gm, no concurrent diseases and hyperbilirubinemia not requiring exchange transfusion. Two groups of newborns were randomly divided into. While the continuous phototherapy group underwent phototherapy for two hours on and 30 minutes off, the intermittent phototherapy group underwent phototherapy for one hour on and one hour off. Results: Patients in the continuous and intermittent phototherapy groups had an average age of 3.231.42 and 3.30+1.59 days, respectively. Their mean baseline bilirubin levels were 15.43mg/dL 1.99 and 15.68mg/dL+1.95, respectively, while their mean follow-up bilirubin levels were 13.79mg/dL 2.15 and 14.23mg/dL+2.29, respectively and the mean difference between the baseline and follow-up bilirubin between both group was 1.63 (p = 0.001) and 1.45 (p = 0.001) respectively. For both groups, the difference in mean age, mean baseline bilirubin and mean follow-up bilirubin was statistically insignificant. For both groups, the mean drop in bilirubin was statistically significant. Conclusion: Intermittent and continuous phototherapies were found to have no difference in therapeutic effect of intermittent and continuous phototherapy.