iarjmsIARJMSIARJMS2708-3594https://doi.org/10.47310/iarjms.2021.v02i01.078To Study Serum Electrolytes and To Correlate with Severity in Patients with DengueSheshan.V.SGuruprasadCShenoyShreedeviKamaraddiKeerthiKumarBackground: Dengue fever is associated with electrolyte disturbances. Hyponatremia and hypokalemia are the commonest electrolyte disturbances. The reason for hyponatremia in classic Dengue fever patients was uncertain. However, it might be the consequence of salt depletion, excess water from increased metabolism, transient inappropriate antidiuretic hormone or the influx of sodium in the cells as a result of dysfunction of sodium potassium pump3. The purpose of the present study was to assess the electrolyte disturbances in Dengue infected patients and to find relation of electrolyte disturbances to complication of Dengue fever. Methods: In this cross sectional study we assessed100 patients admitted with acute stroke in Victoria and Bowring and Lady Curzon hospital during period June 2019 to December 2019. 100 cases of Dengue virus infections were confirmed using Dengue day 1 test kit for detecting dengue antigen. It is a rapid solid phase immune-chromatographic test for the qualitative detection of Dengue NS1 antigen and differential detection of IgM and IgG antibodies to Dengue virus. Serum Sodium and potassium were estimated. Serum electrolyte levels are correlated with Dengue severity. Results: Out of 100 subjects, 3 were having dengue shock syndrome; 28 were having dengue with warning signs and 69 were having dengue without warning signs Majority of patients were males (73) while (27) were female patients. Out of 3 subjects having dengue shock syndrome, all the 3 subjects were females. Fever was found to be the most common clinical presentation in 97 patients (97.9) followed by myalgia in 69 patients (69.6%), headache in 59 patients (59.5%), skin rash in 27 patients (27.27). In the present study, Median sodium levels were high in group having dengue without warning signs (137) followed by dengue with warning signs (131) and dengue shock syndrome (124). Out of 100 subjects, 31 had mild hyponatremia, 7 had moderate hyponatremia and 62 had normal Sodium scores. Chi-square test showed significant association between sodium and dengue severity (c2 = 34.82, p = 0.00). Median Potassium levels were high in group having dengue without warning signs (3.9) followed by dengue with warning signs (3.75) and dengue shock syndrome (3.7). Out of 100 subjects, 35 had mild hypokalemia, 1 had moderate hypkalemia and 84 had normal potassium scores. Chi-square test showed no significant association between potassium and dengue severity. Conclusion: Hyponatremia was the most frequent electrolyte disturbance. Mild hyponatremia and mild hypokalemia were more common among patients of Dengue without warning signs, whereas moderate and severe hyponatremia were more common among Dengue with warning signs and severe Dengue.