iarjmsIARJMSIARJMS2708-3594https://doi.org/10.47310/iarjms.2021.v02i01.004Nanotechnology- Advancements in Periodontal Disease Treatment: A ReviewSamjothaDharmaNagarathnaDVPeriodontal disease is a chronic, multifactorial, inflammatory disease associated with dysbiotic biofilm of the plaque and is characterized by progressive destruction of dental attachment apparatus. The goal of periodontal disease treatment is to achieve complete regeneration of the periodontal tissues (cementum, periodontal ligament and bone). In recent years the advent of Nanotechnology has provided a promising insight into field of Dentistry and in particular Periodontology and Implantology. Due to the small size of nanoparticles, they are able to deliver the drug to particular tissues, cells or pathogens in the periodontal pockets and also act as a regenerative material. This review focuses on the experimental studies of various authors and their usage of nanomaterial in managing periodontal diseases, including diagnosis and treatment.