iarjmsIARJMSIARJMS2708-3594https://doi.org/10.47310/iarjms.2020.v01i02.035A Rare case of Anophtalmia Plus Syndrome (APS) or Fryns AnophtalmiaThéraJPTiamaJMKonipoACongenital anophthalmia is a serious but rare eye deformities. It may be combined with other organ deformities often as part of a specific syndrome. We are reporting the case of a 07-month-old infant with congenital left anophthalmia associated with a cleft lip and palate: Anophtalmia Plus Syndrome (APS).