iarjmsIARJMSIARJMS2708-3594https://doi.org/10.47310/iarjms.2020.v01i02.009Clinical Profile and Risk Factors of Coronary Artery Disease (CAD) Patients in Sub-Himalayan RegionUshyenderSharmaSharmaMahajanBhartiAmitSachdevaAcute Coronary Syndrome (ACS) which is considered to be disease of older people over 45 yrs of age but is being observed in an increasing number of younger patients. The objectives of present study were to assess the clinical and risk factor profile of patients of ACS aged<45 years admitted in CCU of Department of Medicine, I.G. Medical College, Shimla. Materials and Methods: The present hospital-based study was done in patients of young CAD admitted from 1st June 2013 to 31st May 2014. Total 50 patients of ACS aged<45 years were studied. Demography, various risk factors, clinical presentation and outcome were studied. Results: Of total 50 patients of ACS aged<45 years, mean age of presentation was 40.28 years (SD 4.699), 70% were in the age group 35-45 and 56% were from rural background. Forty-five were males and 5 were females. Chest pain (100%), sweating (80%), palpitations (36%) Syncope/pre syncope (34%), dyspnoea and vomiting (14%) were main clinical presenting complaints. Seven (14%) had atypical presenting complaints. STEMI (46%) was most common sub type followed by NSTEMI (28%) and USA (26%). Smoking was most significant risk factor associated with ACS. Dyslipidaemia (total cholesterol, LDL-C), alcohol abuse, hypertension, metabolic syndrome and Prediabetes/Diabetes Mellitus were other risk factors associated. Eleven total 23 patients of STEMI were successfully thrombolysis, 11 presented after more than 12 hours. In ECHO and ECG based findings LAD territory was most commonly involved followed by RCA territory and combined involvement. Fourteen (28%) patients had ejection fraction<60%. Forty-seven (94%) percent improved after treatment and mortality rate was 2%. Conclusion: In ACS in young, there was male preponderance; STEMI was most common with LAD most common territory involved. Smoking was most significant risk factor. ASC in young was associated with a favourable prognosis.