iarjasfrIARJASFRIARJASFR2789-598Xhttps://doi.org/10.47310/iarjasfr.2021.v01i01.006Gene Drive and Its Tools Usage for EditingKomalJavedResearchers are studying gene drive from the 1880s. Gene drive gives the organisms with modified genetic makeup, who can meet the challenges of this ecosystem in a better way as compared to the non-modified who do not have this potential. It is the field of genetic engineered tools. With the help of gene drive phenomenon, we can protect the endangered and threatened species. Applications of the gene drive are enormous and mind blowing. There are different tools of the gene drive like ZFNs, TALENs and CRISPR/Cas9, These are the most common sources of gene drive which provide us excellent options of editing. CRISPR/Cas9 has made the editing more easy and efficient due to the production of very less chances of off target cuts. Nowadays, CRISPR/Cas9 is considered as the most authentic and useful way of editing. But simultaneously, the marvelous technique of the CRISPR/Cas9 requires further laboratory and field research for production of the environmental friendly results.  So, the plenty of the efforts are mandatory to make in the field of this revolutionary technique, the compelling reason for doing these practices is just to cope with the case of different climate conditions and the diverse variety of the organisms.