srjcmsSRJCMSSRJCMS2788-8851https://doi.org/10.47310/srjcms.2021.v01i01.010Lyophilized Platelet-Rich Plasma: Advantages and Applications in COVID-19 PatientsMahajanPradeepKulkarniAjitSubramanianSwethaMahajanSanskrutiThe current coronavirus disease 19 (COVID-19) pandemic is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus and its variants. Though various vaccines are now available in the market and become effective in reducing the severity of disease and hospitalization, still for those who are infected with SARS-CoV-2 there is no effective treatment to deal with this health emergency, and therefore, there is an urgent need for the new treatments. The design of new therapies must be focused not only on the elimination of the virus but also on the recovery of the affected lung tissue and the avoidance or reduction of the severe sequels. In that sense, treatments based on regenerative medicine and specifically platelet-rich plasma (PRP) could be found suitable and effective to tackle this disease. Lyophilized PRP in nebulized form can be effective as it directly enters the lungs and unique properties of PRP such as immunomodulatory, anti-inflammatory, angiogenic, anti-fibrotic and anti-apoptotic, anti-bacterial properties as well as stimulation of different cells, etc. exerts their effect to improve the health condition rapidly.  However, further studies are warranted to prove its efficacy. In this review, we used words like COVID-19, drugs used in the nebulized form in COVID-19, platelets, the role of platelets in various disease conditions, platelet-rich plasma, nebulization, lyophilization for selecting, extracting, and synthesizing data using Google search engine, PubMed search. This review is focused on the advantages and applications of LPRP in nebulized form as a treatment in COVID-19 patients.