iarjpIARJPIARJP2709-9512https://doi.org/10.47310/iarjp.2022.v03i01.004A review on Rheumatoid Arthritis and It’s PathogenesisJyotiShekhawatGargAjayKumarTiwariPiushSharmaShikhaJakhotiaRheumatoid arthritis could be a chronic inflammatory disorder that may affect over just your joints. In some people, the condition can damage a good style of body systems, including the skin, eyes, lungs, heart and blood vessels. An autoimmune disease occurs when your system mistakenly attacks your own body's tissues. Unlike the wear-and-tear damage of osteoarthritis, atrophic arthritis affects the liner of your joints, causing a painful swelling which will eventually lead to bone erosion and joint deformity. The inflammation related to rheumatism is what can damage other parts of the body additionally. While new styles of medications have improved treatment options dramatically, severe rheumatism can still cause physical disabilities. Rheumatoid arthritis could be a systemic disease that always affects the foot and ankle. Approximately 20% of patients with rheumatism present initially with foot and ankle symptoms, and most patients will eventually develop foot and ankle symptoms. Although early intervention includes conservative measures, operative treatment often is required to adequately treat rheumatoid patients. Treatment of foot and ankle problems in patients with autoimmune disorder is directed to maintaining ambulatory capacity.