iarjpIARJPIARJP2709-9512https://doi.org/10.47310/iarjp.2021.v02i01.003Novel studies on Anti Apoptosis inhibitors as a Preventive Measure for CancerWaghJyotiGorakhCancer is one of the leading diseases that is affecting large number of population in the world. Apoptosis represents a major causative factor in the development and progression of cancer. The challenge currently facing is to translate information gained about mechanisms of aberrant cell death control in tumors into new therapeutic opportunities. The path for accomplishing this has been illuminated by basic research. Damage in the Apoptotic pathway may leads to cause of cancer. Apoptotic signaling pathway which acts a novel drug target for cancer. Cellular FLICE-like inhibitory protein(c-FLIP) is a catalytically inactive Caspase-8 homologue. Laetrile, commonly known as Vitamin B-17 or Amygdaline, is a natural chemotherapeutic agent found in over 1,200 plants. According to Dr. Krebs, we need a minimum of 100 mg/day of vitamin B-17 too nearly guarantee a cancer free life. Foods that contain vitamin B-17 are apricots seeds, Cassava root, Sorghum etc. In the present study we have considered c-Flip protein for homology modeling and further ligand based studies to find out best c-flip inhibitors. This protein is not yet studied because its structure is for not available in PDB so we modeled it and then docked it for finding the compound. Further we searched it in a natural source. After finding the compound same feature like Amygdaline we selected its natural source Cassava and Sorghum then processed it for extracting the same.