iarjimphIARJIMPHIARJIMPH2709-331Xhttps://doi.org/10.47310/iarjimph.2022.v03i01.013Hospital based Comparative Study of Single Clip Laparoscopic Cholecystectomy (SCLC) and Clipless Laparoscopic Cholecystectomy (CLLC)AnshuAttriParulSharmaUKChandelBhavashDevkaranAshokKaundalKartikSyalBackground: Benefits for use of Clipless Laparoscopic Cholecystectomy (CLLC) technique using Absorbable suture material and Single Clip Laparoscopic Cholecystectomy (SCLC) using harmonic scalpel are Less operative time, Less bleeding, Early postoperative recovery, Less spillage of stones, Less chances of converting into open cholecystectomy, Less pain post operatively and Less amount of CO2 used. This study was undertaken to compare the advantages of Single clip laparoscopic cholecystectomy (SCLC) and Clipless Laparoscopic Cholecystectomy (CLLC). Material and Methods: This prospective randomized study was conducted in the Department of Surgery IGMC, Shimla over a period of 1 year starting from 1st july 2019 to 30th june 2020. In this study 100 consecutive patients of symptomatic cholelithiasis confirmed by USG reporting were participated and randomized into 2 groups of 50 each. Group 1 patients underwent SCLC and Group 2 patients underwent CLLC. Outcomes were measured in terms of operative time, intra operative stone spillage, intra operative blood loss, amount of CO2 used, post-operative pain, conversion into open cholecystectomy and post-operative complications. Results: Among the total 100 patients, 24 were males and 76 were females. Among them, 10 males and 40 females underwent single clip laparoscopic cholecystectomy (SCLC) while 14 males and 36 females underwent Clipless laparoscopic cholecystectomy (CLLC). In between two groups, mean age of males were 48.50±14.49 and females were 46.73±16.16 in SCLC group while mean age of males were 53.07±18.96 and females were 44.44±15.41 in clipless laparoscopic cholecystectomy group. Present study showed that there was significant more Operative Time and more Mean CO2 used in CLLC group as compared to SCLC group. In the study although there was more Approx. Blood Loss, more Intra Op. Stone spillage and more Use of Drain, more Average Length of hospital stay, more Post Op. Complications but less Average pain score at 6 and 24 hours in CLLC group as compared to SCLC group but this difference was not statistically significant.  Similarly, in both groups equal number of patients Converted to Open Cholecystectomy. Conclusion: Study concluded that there was no statistically significant difference among both groups except for Operative Time and Mean CO2 used which was significantly more in CLLC group as compared to SCLC group.