iarjimphIARJIMPHIARJIMPH2709-331Xhttps://doi.org/10.47310/iarjimph.2022.v03i01.012Comparative Study of Two Clip Laparoscopic Cholecystectomy (TCLC) and Clipless Laparoscopic Cholecystectomy (CLLC)AnshuAttriParulSharmaUKChandelBhavashDevkaranAshokKaundalKartikSyalBackground: Laparoscopic cholecystectomy (LC) is the gold standard for the treatment of gallstone disease.This study was undertaken to compare the advantages of two clips laparoscopic cholecystectomy (TCLC) and Clipless Laparoscopic Cholecystectomy (CLLC). Material and Methods: This prospective randomized study was conducted in the Department of Surgery IGMC, Shimla over a period of 1 year starting from 1st july 2019 to 30th june 2020. In this study, 100 consecutive patients of symptomatic cholelithiasis confirmed by USG reporting were participated and randomized into 2 groups of 50 each. Group-1 patients underwent TCLC and Group-2 patients underwent CLLC. Outcomes were measured in terms of operative time, intra operative stone spillage, intra operative blood loss, amount of CO2 used, post-operative pain, conversion into open cholecystectomy and post-operative complications. Results: Among the total 100 patients, 28 were males and 72 were females. Among them, 14 males and 36 females underwent TCLC while 14 males and 36 females underwent CLLC. In between two groups, mean age of males were 45.36±14.53 and females were 45.25±15.97 in TCLC group-while mean age of males were 53.07±18.96 and females were 44.44±15.41 in CLLC group. Present study showed that there was significant more Operative Time and more Mean CO2 used in CLLC group-as compared to TCLC group. In the study although there was more Approx. Blood Loss, more Intra Op. Stone spillage and more Use of Drain, more Average Length of hospital stay, more Post Op. Complications, more Average pain score at 6 but less Average pain score at 24 hours in CLLC group-as compared to TCLC group-but this difference was not statistically significant. Similarly, in both groups equal number of patients Converted to Open Cholecystectomy. Conclusion: Study concluded that there was no statistically significant difference among both groups except for Operative Time and Mean CO2 used which was significantly more in CLLC group-as compared to TCLC group.