iajabmsIAJABMSIAJABMS2709-3298https://doi.org/10.47310/iajabms.2021.v02i02.009Comparative Study of Heavy Metals Concentration in Blood and Urine of Chronic Kidney Disease Patients and Healthy Persons in Gashua, Yobe State, NigeriaAminuH.TUbaGadakaM.AChronic kidney disease (CKD) is a condition that is characterized by a gradual loss of kidney function over time, and when it progresses can lead to kidney failure. The number of chronic kidney patients is increasing annually in Gashua Yobe State. Therefore this research work intend to compare the level of heavy metals in blood and urine of chronic kidney disease patients and healthy persons in Gashua using atomic absorption spectroscopic techniques. The concentration of Zn, Pb, Cd, Fe, Ni and Cr in the blood and urine of males and females CKD patients, healthy persons, and WHO permissible limit were compared. Based on the findings of this research it revealed higher metals concentration in the blood of males CKD patients Pb(0.087mg/l), Ni(0.075mg/l), Fe(0.133mg/l) and Cd(0.108mg/l) but the concentration of Zn(0.108mg/l) and Cr(0.238mg/l) were higher in the blood of male healthy persons. While for females CKD patients, the concentration of Pb(0.04mg/l), Ni(0.039mg/l), Fe(0.223mg/l), Cr(0.112mg/l) were higher than that of females healthy persons but the concentration of Zn(0.062mg/l) and Cd(0.247mg/l) were higher in the blood of female healthy persons as compared with that of female CKD patients. On the other hand the concentration of Zn, Pb, Cd, Fe, Ni and Cr in the urine of males and females CKD patients were found to be higher than that of healthy persons. The concentration of heavy metals in the blood and urine of CKD patients detected in these research were higher than the WHO permissible limit while for healthy persons the concentration of the heavy metals in the blood were above the WHO permissible limit and the heavy metals such as Zn, Ni, and Pb are higher than WHO standard but Cd, Fe and Cr were within the WHO permissible limit in the urine of males while for the urine of females healthy persons it showed that the concentration of Zn, Ni, Cd, Fe and Cr were within the WHO permissible limit except Pd which is higher than WHO standard.