iajabmsIAJABMSIAJABMS2709-3298https://doi.org/10.47310/iajabms.2021.v02i01.001A descriptive study of ocular findings among the patients of Pseudoexfoliation without Glaucoma attending OPD clinic in a tertiary care hospital in Western Himalayan RegionSharmaSSharmaRLSharmaVResident, Department of Ophthalmology, IGMC Shimla, Himachal PradeshProfessor & Head, Department of Ophthalmology, IGMC Shimla, Himachal Pradesh.Associate Professor, Department of Ophthalmology, IGMC Shimla, Himachal Pradesh.Pseudo exfoliation (PEX) syndrome is a complex systemic disorder of the extracellular matrix primarily affecting the eye and visceral organs characterized by the deposition of fibrillar material on all anterior segment structures.Ocular involvement in PEX primarily manifests with anterior segment findings.The present cross-sectional descriptive study was conducted in the Department of Ophthalmology, Indira Gandhi Medical College, Shimla among the selected patients of pseudo exfoliation with glaucoma over a period of one year with an objective of describing the ocular as well as intra-ocular findings among them. There were 46 study participants of which there were 24 males and 22 females with the mean age of 68.43±9.88 years. Majority of the patients had an IOP ranging between 10-20 mm Hg and a vertical cup-disc ratio between 0.3 and 0.4. The overall mean RNFL Thickness was found to be 89.47±13.52 µm.Mean Central Corneal Thickness (CCT) in our study participants was 496.74±30.873 µm, Mean Endothelialcell density (ECD) was 2586.33±505.156 cells/mm2, Mean Coefficient of variation (CV) 37.37 ± 4.25%, whereas the Mean Hexagonal Ratio (HR) was found to be 29.74 ± 9.15 %. There were more morphological abnormalities of corneal endothelial cells and decrease in RNFL thickness in patients with PEX. The RNFL thickness and Endothelial Cell Density seem to be reduced, thus leading to progressive corneal damage.