iarjmcrIARJMCRIARJMCR2709-3220https://doi.org/10.47310/iarjmcr.2022.v03i01.008Acute Pancreatitis in a Patient with Parathyroid Adenoma- An Uncommon Case ReportSantoshD.HazareInduYadavDepartment of Gastroenterology, Jawaharlal Nehru Medical College, Kaher, IndiaBackground: Acute pancreatitis is a common clinical entity, common causes being chronic alcohol consumption and gallstones. Acute episode of pancreatitis is uncommonly reported with a case of primary hyperparathyroidism. So, here we present a 33-year-old male who presented with acute abdomen caused by acute pancreatitis with no history of gallstones and alcohol consumption. He was further investigated for other uncommon causes of pancreatitis and found to have hyperparathyroidism caused by parathyroid adenoma. Hence, we suspect hypercalcemia induced by parathyroid adenoma can be a causative factor for the acute pancreatitis patients. Case Summary: We are reporting a case of 33-year-old male who presented with chief complaint of severe pain in epigastric region associated with vomiting and mild abdominal distension. With clinical, biochemical and image modalities a confirmed diagnosis of acute pancreatitis was made. On detailed investigations he was found to have hypercalcemia and increased parathyroid hormone levels. Patient was managed conservatively initially but due to repeated episodes of pain abdomen and persistent severe hypercalcemia with significant ECG changes showing bradycardia and prolonged QT interval, parathyroid adenoma was excised and renal stones were removed. After parathyroid excision patient improved drastically and parathyroid hormone levels came to a normal range post-operatively but hypocalcemia was seen post operatively which was medically managed successfully. Conclusion: Acute pancreatitis is a uncommon first clinical manifestation of hyperparathyroidism induced hypercalcemia.