iarjmcrIARJMCRIARJMCR2709-3220https://doi.org/10.47310/iarjmcr.2022.v03i01.007Schwannoma of the Ileum: A Rare Localization. Le Schwannome De L’ileon: Une Localisation RareDialloKadidiatouFollyDyattaMayomboKévinNgueleNdjotaOparadjiJosephRichardTsagoulelaBigwagouArmandoIpoukaDoussiemouSerginaIntroduction: Schwannoma is a tumor of nerve origin that develops at the expense of Schwann sheath cells. It has a ubiquitous distribution in the body. Located in the digestive tract, together with leiomyomas, leiomyosarcomas and leiomyoblastomas, it constitutes the group of GISTs. The rarity and risk of malignant transformation of this condition prompted us to report a case observed at the University Hospital Center of Libreville. Observation: EOS, 58 years old, with a history of bilateral ovarian cystectomies, had consulted for cessation of gas matter, with bloating and abdominal pain. Clinical examination revealed an occlusive syndrome without a palpable mass. The ASP had revealed hailstorm-like hydro-aeric levels. Surgical exploration revealed a large solid obstructive ileal mass located 50 cm from the ileocecal junction with dilation of the loops upstream. A segmental carcinological resection with anastomosis in one step was performed. Histological analysis of the specimen revealed a low-grade malignant schwannoma with positive PS 100 antibody. The post-operative course was straightforward. The patient was discharged on D10 postoperative. The CT scan performed after 3 months was unremarkable. Conclusion: schwannoma is a rare condition, as is its intestinal location. The treatment is surgical. Surveillance is necessary, linked to the risk of recurrence and malignant transformation.