iarjmcrIARJMCRIARJMCR2709-3220https://doi.org/10.47310/iarjmcr.2021.v02i01.021A Case of a Large/Giant Gallbladder Stone Retrieved During Cholecystectomy at a Tertiary Care Centre in North India with Review of LiteratureTajamulRashidJavedAltafMusharrafHusainBackground: Gallbladder stone disease is a very common problem encountered by general surgeons thereby making cholecystectomy one of the most frequently surgical operations performed across the globe. The size of stone may vary from few millimetres to as large as the size of a golf ball. The size of the stone can pose technical challenges to the surgeon especially during laparoscopic cholecystectomy. Case Report: A 63 years old male presented to our OPD with chief complaints of recurrent right upper abdominal pain & dyspepsia for 6 months. An ultrasound of whole abdomen was suggestive of single gallbladder stone of approximately 5cm size. Laparoscopic converted to open cholecystectomy was done. The stone retrieved from the gallbladder had almost replaced whole of the gallbladder and was found to be approximately of the size of 7x2.5 cm, making it one the largest gallbladder stones reported in literature.Conclusion: Gallbladder stone disease is a very common entity. Incidence of very large gallstones is rare especially >5 cm. Larger the size of the stone; higher the risk of complications. Laparoscopic cholecystectomy is a standard treatment for gallstone disease, however in case of large stones laparoscopic cholecystectomy may be limited by technical factors including grasping gallbladder wall, obscured Calot’s triangle anatomy, dissection and delivery of gallbladder specimen at the end of the procedure.