iarjmcrIARJMCRIARJMCR2709-3220https://doi.org/10.47310/iarjmcr.2020.v01i01.007HSV6 as a Cause of Severe Complicated Meningo-Encephalitis in a Lebanese Immunocompotent PatientImadChokrKhadijeElSabehLeaChokrOunssiHammoud. OussamaSkafiRanadGergesRouwaydaDanaBassemAbouMerhiRayaneMahfouzHHV-6 constitutes a widely spread viral infection among young children population with a seroprevalence of > 80% in children > 2 years of age [1]. HHV-6 is an enveloped DNA virus belongs to the β-herpes virus family and, together with its closest homologue HHV-7, forms the roseoloviruses subfamily (2). A wide range of clinical manifestation of HHV-6 has been described which may vary with age and immune status of a child including acute febrile illness with or without rash, Roseola Infantum, febrile convulsion, meningo-encephalitis, hepatitis and mononucleosis-like illness, etc. Here we report the case of a 2 years old boy previously healthy who presented with fever, lethargy, decreased level of consciousness and with neck stiffness, diagnosed clinically with severe meningo-encephalitis and confirmed on brain MRI. Human Herpes Virus 6 was the etiology of his encephalitis, verified by his blood neuro-9 PCR.