iarjaccIARJACCIARJACC2709-1880https://doi.org/10.47310/iarjacc.2022.v03i02.070Evaluation of Adverse Effects After Intravenous Ferric Carboxymaltose and Iron Sucrose in the Treatment of Iron Deficiency Anemia in PregnancyAnkitaThakurBishanDhimanNishiSoodSudarshanSharmaSonaliChauhanJunior Resident, Department of Obstetrics & Gynaecology, Kamla Nehru Hospital, IGMC, Shimla, (H. P.), IndiaProfessor and Head, Department of Obstetrics & Gynaecology, Kamla Nehru Hospital, IGMC, Shimla, (H. P.), IndiaAssociate Professor, Department of Obstetrics & Gynaecology, Kamla Nehru Hospital, IGMC, Shimla, (H. P.), IndiaProfessor and Head, Department of Pathology, I.G.M.C Shimla, (H. P.), IndiaJunior Resident, Dept of Obstetrics and Gynecology, Kamla Nehru Hospital, IGMC, Shimla, (H. P.), IndiaBackground: Present study was done with the objective to compare the adverse effects after Intravenous Ferric Carboxymaltose and Iron Sucrose in the treatment of Iron Deficiency Anemia in Pregnancy. Material and Methods: This was a prospective study conducted in the department of Obstetrics and Gynaecology, Kamla Nehru State Hospital for Mother and Child, Indira Gandhi Medical College Shimla from 1st June 2019 to 31st May 2020.86 antenatal women with iron deficiency anemia were included in the study. The subjects were randomized into two equal groups and one group received intravenous ferric carboxymaltose whereas other group received intravenous iron sucrose. Results: The subjects in our study were observed for development of adverse reactions following treatment with intravenous ferric carboxymaltose and iron sucrose. Out of 43 subjects in FCM group, 4.7% developed local adverse reactions and none of the subjects developed systemic reactions. Whereas in ISC group out of 43 subjects, 7% developed local adverse effects and 4.7% developed systemic adverse reactions. The difference between the two groups was statistically significant. Conclusion: The present study concluded that ferric carboxymaltose was associated with a better safety profile compared to iron sucrose.